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  • Overall Score: 3.5/10

Oxy-Burn is a natural fat burner from Biothrive, which has whipped up a bit of a buzz on Amazon. Amazon can be a great place to buy supplements, but fair to say their reviewing system isn’t exactly fool proof.

Oxy Burn

That means before buying you’ve really got to investigate properly to find out if you’re dealing with real satisfied customers or a marketing department.

Or if all that sounds like too much work you could just let us do it for you then read this review.

Oxy-Burn makes has 2 simple aims: speed up metabolism and burn fat. Sounds ideal, except it does this by using 3 proprietary blends. That means no individual amounts for ingredients, just a mix and overall volume.

Knowing that individual doses are right is key, so this is frustrating, but let’s take a closer look anyway.

How Does It Work?

At a Glance

  • Green tea, Yohimbie & (supposedly) Rapberry Ketones to burn fat.
  • Caffeine, Acacia Rigadula & Synephrine to boost metabolism.
  • Phenylethylamine, Fursultiamine & Tyrosine to help energy and focus.

We’ll look at the pros and cons of these choice up close later after the overall scores…

The Scores

The Scores

There are some serious problems with this formula. Even the good things like green tea and yohimbe have question marks over them because we don’t know the amount. And although there are possibly some good energy boosters here, the recent scandal over Acacia Rigidula and  issues with synephrine, make it a risky choice


Oxy-Burn is cheap, but there are times when you get what you pay for. Here you might not even get that. Given our above concerns we’re inclined to suggest that however much money their asking, it’s probably best saved.


This supplement is made in the U.S so you would assume complies with GMC guidelines. But with the use of proprietary blends hiding exact doses and the FDA’s stance on Acacia Rigidula, credibility takes a hit.


We’re left to rely largely on the questionable amazon review section for testimonials and even those are pretty split. They range from the suspiciously perfect too those reporting some of the side effects we warned about. Not exactly a vote of confidence.


We found it pretty hard to dig up any information on BioThrive apart from the fact that they’re based in California and that their products are GMP registered. This is not enough to give a rounded view of the company and is a real disappointment as disclosure is so valuable in this industry.


How Many Servings A Day?

Users take just a single serving a day to get the best out of Oxy-Burn.

We’re always suspicious when we hear this. One serving to burn fat for a whole day? That’s a bit of a stretch. 3-4 servings a day is what you should be looking for to keep active ingredients topped up and the effects ticking over.

What About Side Effects?

This is a real worry. If synephrine raises your blood pressure you could be at increased risk of heart attack or stroke. Some users have also reported sickness as a result of a synephrine and caffeine mix.

Too much yohimbe causes anxiety and stomach problems so you need to be careful there too.

Also if the FDA is warning that PEA in Acacia Rigidula is simmilar to amphetamine, we can’t rule out its side effects. Shaking, restlessness, headaches etc.

Where Can I Get Oxy-Burn?

Customers will find Oxy-Burn at Amazon for just under $20, which buys a month’s supply.

Oxy-Burn Ingredients – In Detail

Ingredients - In Detail

Caffeine / Caffeine Anhydrous

Caffeine / Caffeine Anhydrous

The first burner regular. Caffeine is a great choice for two reasons; firstly it speeds up your metabolism, burning through far more fat, and secondly it provides energy to help you avoid the slumps that normally come with a low calorie diet.

The 'Anhydrous' part refers to the fact that the water is removed to leave a white, crystalline powder with concentrated potency.


Phenylethylamine HCI

Phenylethylamine HCI

Though completely natural, this ingredient is often referred to informally as the love drug due to marked mood boosting powers observed in some studies. So much so that it is sometimes utilized as part of treatment for depression and anxiety. Besides this it has also shown an ability to increase focus and concentration.


Acacia rigidula

Acacia rigidula

This herb is credited with helping to improve mood and speed up metabolism. It has the potential to stimulate useful hormones for weight loss such as noradrenaline. All that would be great, except in 2015 the FDA warned that BMPEA found in Acacia rigidula is not natural. BMPEA is an amphetamine like compound, similar to the banned Ephedrine. Oxy-Burn contains 25% PEA so until this is cleared up we’d avoid the gamble.




An ingredient included to aid cognition. In clinical trials it has displayed modest benefits with conditions like Alzheimer’s and some cases of autism, so does appear to help the overall health of the brain.

In studies on rats it has shown it can boost performance and reduce fatigue, but human trials have been mixed so far.




Aliases : Tyrosine

No direct fat burning benefits in this case, but it does promote feel good hormones such as dopamine and in studies has shown it is able to improve both cognition and focus.

Potentially helpful for getting your head in the game on those days when you’d rather do anything but workout.



Green Tea

Green Tea

Key to any fat burner’s effectiveness is it's thermogenic profile and they don’t come much more impressive than this powerful antioxidant. Green Tea’s catechins stimulate a fat burning hormone called norepinephrine, which naturally raises the body temperature, vastly increasing the number of calories burnt.


Raspberry Ketones

Raspberry Ketones

A fad ingredient and a total waste. Caused a real stir in the fat burning world for a short time after being featured on Dr Oz’s show as the next big thing, but in reality has only managed results in lab rats at absolutely huge doses. If these amounts were to be scaled up for humans we would need multiple grams.


Synephrine HCL

Synephrine HCL

Aliases : Bitter Orange Extract

Sometimes called Bitter Orange Extract, this ingredient has demonstrated the potential to boost both energy and metabolism, albeit somewhat inconsistently. It has a significant downside however, when combined with caffeine, synephrine can provoke some serious side effects and may pose significant health risk.




Yohimbe is an effective fat burner in the right dose because it blocks the alpha receptors in the brain which limit fat burning. Too much yohimbe can cause side effects such as dizziness and nausea.


Anything Missing?

Apart from exact amounts of each ingredient on the label, Oxy-Burn could also do with more natural appetite contol


This burner is a case of the good, the bad and the possibly downright dangerous. It may be cheap, but most people use natural supplements so they don’t have to worry about what they’re taking.

Studies Quoted in the Review

  1. Acheson KJ, Zahorska-Markiewicz B, Pittet P, Anantharaman K, Jéquier E. Caffeine and coffee: their influence on metabolic rate and substrate utilization in normal weight and obese individuals. (1980)
  2. Sabelli HC, Fawcett J, Gusovsky F, Javaid JI, Wynn P, Edwards J, Jeffriess H, Kravitz H. Clinical studies on the phenylethylamine hypothesis of affective disorder: urine and blood phenylacetic acid and phenylalanine dietary supplements. (1986)
  3. Stephen Daniells FDA warns companies with products listing Acacia rigidula as a dietary ingredient Naturaingredients-usa.com (2016)
  4. Suzuki M, Itokawa Y. Effects of thiamine supplementation on exercise-induced fatigue. Institute of Health & Sports Sciences, University of Tsukuba, Japan. (1996)
  5. Webster MJ, Scheett TP, Doyle MR, Branz M. The effect of a thiamin derivative on exercise performance. Department of Physical Education, Western Illinois University, Macomb 61455, USA (1997)
  6. Deijen JB, Wientjes CJ, Vullinghs HF, Cloin PA, Langefeld JJ. Tyrosine improves cognitive performance and reduces blood pressure in cadets after one week of a combat training course. Department of Clinical Neuropsychology, Vrije Universiteit, Amsterdam, The Netherlands. (1999)
  7. Hursel R, Viechtbauer W, Dulloo AG, Tremblay A, Tappy L, Rumpler W, Westerterp-Plantenga MS..The effects of catechin rich teas and caffeine on energy expenditure and fat oxidation: a meta-analysis. Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands (2011)
  8. Morimoto C, Satoh Y, Hara M, Inoue S, Tsujita T, Okuda H.Anti-obese action of raspberry ketone Department of Medical Biochemistry, Ehime University School of Medicine, Shigenobu-cho, Onsen-gun, Ehime, Japan (2005)
  9. Hansen DK, George NI, White GE, Pellicore LS, Abdel-Rahman A, Fabricant D; Food and Drug Administration.Physiological effects following administration of Citrus aurantium for 28 days in rats. Division of Personalized Nutrition and Medicine, U.S. FDA/NCTR, 3900 NCTR Rd., Jefferson, AR 72079, USA.(2012)
  10. Ostojic SM Yohimbine: the effects on body composition and exercise performance in soccer players. Institute of Sports Medicine, Sports Academy, Belgrade, Serbia and Montenegro. (2008)

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